Pumpkin

Additive

Sodium nitrate

Curing agent in processed meats; converts to nitrite.

Moderate concern · Limited evidence

Converts to nitrite in cured meat and the body; linked to colorectal cancer.

Consider limiting, or compare alternatives.

Reviewed Oct 2, 2026

Evidence and sources

Added nitrate is converted to nitrite, which can form N-nitroso compounds. IARC classifies ingested nitrate under conditions that lead to these compounds as probably carcinogenic to humans (Group 2A). In 2022 France's food safety agency confirmed a link between nitrite and nitrate exposure and colorectal cancer.

Nitrate from vegetables hasn't shown the same link. A 2026 French cohort study linked potassium nitrate additives to breast and overall cancer, but observational studies can't prove cause. The amount here isn't declared.

Limited evidence · Presence only; amount unknown · General population

  1. IARC Monographs Volume 94: Ingested nitrate and nitrite (Group 2A under conditions that result in endogenous nitrosation), International Agency for Research on Cancer
  2. Reducing dietary exposure to nitrites and nitrates, French Agency for Food, Environmental and Occupational Health & Safety (ANSES)
  3. Intake of food additive preservatives and incidence of cancer: results from the NutriNet-Santé prospective cohort, The BMJ (Hasenböhler et al.)
  4. Nitrites and nitrates from food additives and natural sources and cancer risk: results from the NutriNet-Santé cohort, International Journal of Epidemiology (Chazelas et al.)
  5. Re-evaluation of sodium nitrate (E 251) and potassium nitrate (E 252) as food additives, European Food Safety Authority